(COLLAGENASE CLOSTRIDIUM HISTOLYTICUM) INJECTION
Collagenase clostridium histolyticum injection is Dupuytren’s contracture medication and Peyronie’s disease medication.
Download the Xiaflex Patient Guide.
XIAFLEX® IS AN IN-OFFICE, NONSURGICAL PROCEDURE
XIAFLEX® can be administered right here in-office at Men’s Health Alaska. This medication is injected directly into the plaque that is causing your erect penis to curve to help break down the plaque.
PEYRONIE’S DISEASE MEDICATION INJECTION SCHEDULE
A treatment course of Xiaflex® consists of up to 4 treatment cycles 6 weeks apart. Set up all injection appointments at the initial consultation. Your healthcare provider will determine how many treatment cycles are appropriate.
In each treatment cycle, you will receive 2 injections of XIAFLEX® on separate days, 1 to 3 days apart. Do not have sex or any other sexual activity between the first and second injections of a treatment cycle.
1 to 3 days after the second injection of XIAFLEX®, you will need to return to the Men’s health Alaska office for a manual procedure that will stretch and help straighten your penis. We will tell you exactly when to come back for this.
In addition, you will perform at-home stretching and straightening activities on your penis for approximately 6 weeks after the manual procedure.
WHAT DO YOU NEED TO DO AT HOME? PENILE MODELING ACTIVITIES
At Men’s Health Alaska, your physician will show you how to stretch and straighten your penis the right way at home after each treatment cycle. You will need to take a few minutes each day to perform gentle stretching and straightening penile modeling activities on your penis, closely following our directions.
There are 2 types of penile modeling activities:
- The first is a gentle stretching activity to be performed when the penis is not hard (erect).
- The second is a gentle straightening activity, which should be performed when the penis is erect without any sexual activity.
Although these activities only take a few minutes, it is important that you follow our instructions and do them every day for approximately 6 weeks after each treatment cycle.
(1) DAILY STRETCHING
Gently stretch your penis 3 times a day. Only stretch your penis if your penis is not hard (erect). With 1 hand, hold the tip of your penis with your fingers. With your other hand, hold the base of your penis with your fingers. Gently pull your penis away from your body to its full length and hold the stretch for 30 seconds. Let go of the tip of your penis and let your penis return to its normal length.
Helpful hint: the stretching activity can be done any time of day when you don’t have an erection. Establishing a routine may make it easier to remember, so try to do the stretching activity at the same time and place each day. Giving yourself privacy may allow you to feel more comfortable and less rushed.
(2) DAILY STRAIGHTENING
Gently straighten your penis 1 time a day. Only straighten your penis if you have an erection that happens without any sexual activity (spontaneous erection). Bending your penis should not cause any pain or discomfort. With 1 hand, hold your penis. With your other hand, gently bend your penis in the opposite direction of the curve. Hold the penis in this more straightened position for 30 seconds, then let go.
